OGFOD2 antibody (Center)

Catalog No. ABIN783391

This Rabbit Polyclonal antibody specifically detects OGFOD2 in WB and EIA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for OGFOD2 antibody (Center) (ABIN783391)

Target: OGFOD2 (2-Oxoglutarate and Iron-Dependent Oxygenase Domain Containing 2 (OGFOD2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OGFOD2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-OGFOD2 Antibody

Binding Specificity: Center

Specificity: This antibody detects OGFOD2 at Center. OGFOD2 antibody is predicted to not cross-react with other TPA1 protein family members. At least three isoforms are known to exist, this antibody will only detect the two larger isoforms.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the center of human OGFOD2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for OGFOD2

Target: OGFOD2 (2-Oxoglutarate and Iron-Dependent Oxygenase Domain Containing 2 (OGFOD2))

Alternative Name: OGFOD2

Background: OGFOD2 is a member of the 2-OG-Fe(II) dioxygenase family which plays an important role in ischemic survival and stress. Like the related protein OGFOD1, OGFOD2 is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. Little is known about the function of OGFOD2, but its similarity to OGFOD1 suggests that it is a novel stress granule component that may play an important proapoptotic role in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.Synonyms: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2, FLJ13491

Gene ID: 79676

NCBI Accession: NP_078899

UniProt: Q6N063