NKX3-2 antibody (Center)

Catalog No. ABIN783403

This Rabbit Polyclonal antibody specifically detects NKX3-2 in WB and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NKX3-2 antibody (Center) (ABIN783403)

Target: NKX3-2 (NK3 Homeobox 2 (NKX3-2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX3-2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-NKX3-2 Antibody

Binding Specificity: Center

Specificity: This antibody detects BAPX1 / NKX3B at Center. BAPX1 antibody is predicted not to cross-react with other NKX homeobox proteins.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the center of human BAPX1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for NKX3-2

Target: NKX3-2 (NK3 Homeobox 2 (NKX3-2))

Alternative Name: BAPX1 / NKX3B

Background: BAPX1 is the mammalian homolog of the Drosophila bagpipe homeobox gene and is expressed in the splanchnic mesoderm and embryonic skeleton. It is one of the earliest developmental markers for the sclerotome portion of the somite and the gut mesentery. BAPX1 is required for normal skeletal development, homozygous inactivating mutations in the BAPX1 gene result in spodylo-megaepiphyseal-metaphyseal dysplasia (SMMD). It has also been suggested to play a role in the proper development of the mammalian gut and is required for distal stomach development as part of a BARX1-dependent pathway.Synonyms: Bagpipe homeobox protein homolog 1, Homeobox protein NK-3 homolog B, Homeobox protein Nkx-3.2, NKX3-2, Nkx-3.2

Gene ID: 579

NCBI Accession: NP_001180

UniProt: P78367