CTNNBL1 antibody (C-Term)

Catalog No. ABIN783411

This anti-CTNNBL1 antibody is a Rabbit Polyclonal antibody detecting CTNNBL1 in WB and EIA. Suitable for Human, Mouse and Rat.

Quick Overview for CTNNBL1 antibody (C-Term) (ABIN783411)

Target: CTNNBL1 (Catenin, beta Like 1 (CTNNBL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNNBL1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CTNNBL1 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects CTNNBL1 at C-term. CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist, this antibody will detect all but isoform b.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 20 amino acid peptide near the carboxy terminus of human CTTNBL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for CTNNBL1

Target: CTNNBL1 (Catenin, beta Like 1 (CTNNBL1))

Alternative Name: CTNNBL1

Background: The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.Synonyms: Beta-catenin-like protein 1, C20orf33, NYD-SP19, Nuclear-associated protein, Testis development protein NYD-SP19

Gene ID: 56259

NCBI Accession: NP_110517

UniProt: Q8WYA6

Pathways: Production of Molecular Mediator of Immune Response