WDR92 antibody (Center)

Catalog No. ABIN783689

The Rabbit Polyclonal anti-WDR92 antibody has been validated for WB and EIA. It is suitable to detect WDR92 in samples from Human and Mouse.

Quick Overview for WDR92 antibody (Center) (ABIN783689)

Target: WDR92 (WD Repeat Domain 92 (WDR92))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR92 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-WDR92 Antibody

Binding Specificity: Center

Specificity: This natibody detects WDR92 / Monad at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 21 amino acid peptide near the center of human WDR92

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for WDR92

Target: WDR92 (WD Repeat Domain 92 (WDR92))

Alternative Name: WDR92 / Monad

Background: WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR92, also known as monad, contains two WD40 repeats is widely expressed in human tissues, especially testis. Overexpression of this protein or its binding partner RNA polymerase II-associated protein 3 (RPAP3) potentiated apoptosis and caspase-3 activation induced by TNF-a and cycloheximide, suggesting that WDR92, together with RPAP3, may function as a novel modulator of apoptosis.Synonyms: WD repeat-containing protein 92, WD repeat-containing protein Monad

Gene ID: 116143

NCBI Accession: NP_612467

UniProt: Q96MX6