TRIP6 antibody (Center)

Catalog No. ABIN783745

This Rabbit Polyclonal antibody specifically detects TRIP6 in WB and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for TRIP6 antibody (Center) (ABIN783745)

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TRIP6 Antibody

Binding Specificity: Center

Specificity: This antibody detects TRIP6 / OIP1 at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human TRIP6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for TRIP6

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Alternative Name: TRIP6 / OIP1

Background: TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-kB activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.Synonyms: OIP-1, OPA-interacting protein 1, TRIP-6, ZRP-1, Zyxin-related protein 1

Gene ID: 7205

NCBI Accession: NP_003293

UniProt: Q15654

Pathways: Cell-Cell Junction Organization