Transmembrane Protein 18 (TMM18) (C-Term) antibody

Catalog No. ABIN783829

This Rabbit Polyclonal antibody specifically detects in WB and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Transmembrane Protein 18 (TMM18) (C-Term) antibody (ABIN783829)

Target: Transmembrane Protein 18 (TMM18)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details

Binding Specificity: C-Term

Specificity: This antibody reacts to Transmembrane protein 18.

Purification: Affinity chromatography

Immunogen: 15 amino acid peptide near the carboxy terminus of human TMEM18.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details

Target: Transmembrane Protein 18 (TMM18)

Alternative Name: TMEM18

Background: Recent studies have examined how overexpression of certain genes enhances the tropism of neural stem cells (NSCs) for gliomas. Overexpression of Transmembrane protein 18 (TMEM18) provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells in vitro and in the rat brain, while functional inactivation of the gene resulted in an almost complete loss of migration activity, suggesting that TMEM18 could be a potential target in NSC-based glioma therapy. Other recent results suggest that among others, the TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, indicating there may be a CNS-related role in predisposition to obesity. Multiple isoforms of TMEM18 are known to exist.Synonyms: Transmembrane protein 18

Gene ID: 129787

NCBI Accession: NP_690047

UniProt: Q96B42