Cathepsin L2 antibody (Internal Region)

Catalog No. ABIN784595

The Rabbit Polyclonal anti-Cathepsin L2 antibody is suitable to detect Cathepsin L2 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for Cathepsin L2 antibody (Internal Region) (ABIN784595)

Target: Cathepsin L2 (CTSL2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin L2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Cathepsin L2 Antibody

Binding Specificity: Internal Region

Specificity: This antibody detects endogenous levels of of fragment of activated CATL2 resulting from cleavage adjacent to Leu114.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from human CATL2. Remarks: Antigen Modification: Internal

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C or lower. Avoid freeze-thaw cycles.

Target Details for Cathepsin L2

Target: Cathepsin L2 (CTSL2)

Alternative Name: Cathepsin L2

Background: Cathepsin V, also known as Cathepsin L2 and Cathepsin U, is a cysteine protease of the papain family. It is expressed as a proenzyme in lysosomes, which can be autocatalytically converted to the mature form at pH 4.0. Cathepsin V is specifically expressed in the thymus, testis, and corneal epithelium.Synonyms: CATL2, CTSL2, CTSU, CTSV, Cathepsin U, Cathepsin V

Gene ID: 1515

NCBI Accession: NP_001188504

Pathways: Toll-Like Receptors Cascades