FGFR1 antibody (N-Term)

Catalog No. ABIN790674

Product Details anti-FGFR1 Antibody

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGFR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Brand: IHC-plus™

Specificity: Reacts with the NH2-terminus of unique NH2-terminal Ig loop of FGFr1. Epitope is within the sequence between glu30 and ala74 of FGFr1a. Reacts with human, rat, and mouse receptor. Other species untested.

Purification: Protein G purified

Immunogen: Recombinant human ectodomain of FGFr1a expressed in E. coli beginning with pro23, antigen contained NH2-terminal gly-ser-pro-gly-ile and C-terminal glu-phe sequences.

Type of Immunogen: Recombinant protein

Clone: M2F12

Isotype: IgG2a

Application Details

Application Notes: Approved: IHC, IHC-Fr, IHC-P (10 μg/mL), IP, WB (1 μg/mL)

Usage: Western blotting: at 1 μg/mL recognizes 10 ng recombinant bacterial, baculo-viral, or native FGFr1. Immunoprecipitation: native, nuclear, recombinant, and ligand-labeled FGFr1. Immunohistochemistry: frozen sections of human glioblastomas, paraformaldehyde fixed cells and nuclei, human myocardial biopsies, FFPE human tissues.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Handling Advice: Aliquot to Avoid freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot to avoid freeze/thaw cycles.

Target Details for FGFR1

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Alternative Name: FGFR1 (FGFR1 Products)

Background: Name/Gene ID: FGFR1
Subfamily: FGF Receptor
Family: Protein Kinase

Synonyms: FGFR1, BFGF receptor, BFGF-R, BFGF-R-1, CD331, Cek1, CD331 antigen, FGFR1/PLAG1 fusion, FLT2, Fgf-flg, FGFBR, FGFR-1, Fms-like tyrosine kinase 2, HBGFR, HH2, Hydroxyaryl-protein kinase, FGF receptor 1, Fms-related tyrosine kinase 2, Proto-oncogene c-Fgr, BFGFR, CEK, FLT-2, HBGF receptor, KAL2, OGD

Gene ID: 2260

UniProt: P11362

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins