CCNDBP1 antibody (AA 281-360)

Catalog No. ABIN872665

This Rabbit Polyclonal antibody specifically detects CCNDBP1 in WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CCNDBP1 antibody (AA 281-360) (ABIN872665)

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCNDBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CCNDBP1 Antibody

Binding Specificity: AA 281-360

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCNDBP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CCNDBP1

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Alternative Name: CCNDBP1

Background:

Synonyms: Maternal inhibition of dferentiation, SECC 8, SSEC 8, CCDB1_HUMAN, CCNDBP 1, Ccndbp1, Cyclin D type binding protein 1, Cyclin-D1-binding protein 1, D type cyclin interacting protein 1, DIP 1, DIP1, GCIP, Grap 2 and cyclin D interacting protein, Grap 2 cyclin D interacting protein GCIP, Grap 2 cyclin interacting protein, Grap2 and cyclin D interacting protein, Grap2 and cyclin-D-interacting protein, Grap2 cyclin D interacting protein GCIP, Grap2 cyclin interacting protein, HHM protein, Human homolog of Maid, MAID, MAID protein, Stage specic embryonic cDNA 8.

Background: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.Tissue specificity: Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.

Gene ID: 23582