ZMYND11 antibody (AA 501-602)

Catalog No. ABIN872692

This Rabbit Polyclonal antibody specifically detects ZMYND11 in ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for ZMYND11 antibody (AA 501-602) (ABIN872692)

Target: ZMYND11 (Zinc Finger, MYND-Type Containing 11 (ZMYND11))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMYND11 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ZMYND11 Antibody

Binding Specificity: AA 501-602

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adenovirus 5 E1A binding protein

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ZMYND11

Target: ZMYND11 (Zinc Finger, MYND-Type Containing 11 (ZMYND11))

Alternative Name: Adenovirus 5 E1A binding protein

Background:

Synonyms: BS69, BRAM1, MRD30, Zinc finger MYND domain-containing protein 11, Adenovirus 5 E1A-binding protein, Bone morphogenetic protein receptor-associated molecule 1, Protein BS69, ZMYND11

Background: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Gene ID: 10771

UniProt: Q15326