KLHL20 antibody (AA 13-100)

Catalog No. ABIN873096

This anti-KLHL20 antibody is a Rabbit Polyclonal antibody detecting KLHL20 in IF (cc), IF (p), ELISA, IHC (fro) and IHC (p). Suitable for Rat.

Quick Overview for KLHL20 antibody (AA 13-100) (ABIN873096)

Target: KLHL20 (Kelch-Like 20 (KLHL20))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL20 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KLHL20 Antibody

Binding Specificity: AA 13-100

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLHL20

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KLHL20

Target: KLHL20 (Kelch-Like 20 (KLHL20))

Alternative Name: KLHL20

Background:

Synonyms: Kelch like ECT2 interacting protein, Kelch like protein 20, Kelch like protein X, Kelch mot containing protein, Kelch-like ECT2-interacting protein, Kelch-like protein 20, Kelch-like protein X, KHLHX, KLEIP, KLH20CHUMAN, KLHL20, KLHLX, RP3-383J4.3.

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases.

Gene ID: 27252