COMMD7 antibody (AA 81-170)

Catalog No. ABIN873293

The Rabbit Polyclonal anti-COMMD7 antibody has been validated for ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It is suitable to detect COMMD7 in samples from Human.

Quick Overview for COMMD7 antibody (AA 81-170) (ABIN873293)

Target: COMMD7 (COMM Domain Containing 7 (COMMD7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMMD7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-COMMD7 Antibody

Binding Specificity: AA 81-170

Predicted Reactivity: Human,Mouse,Rat,Dog,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COMMD7

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for COMMD7

Target: COMMD7 (COMM Domain Containing 7 (COMMD7))

Alternative Name: COMMD7

Background:

Synonyms: C20orf92, Chromosome 20 open reading frame 92, COMM domain containing 7, COMM domain containing protein 7, COMMD 7, dJ1085F17.3, FLJ14987, MGC33315, OTTHUMP00000030609, COMD7_HUMAN.

Background: COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The prototype of this family, MURR1/COMMD1, suppresses NFkB by affecting the association of NF-kappaB with chromatin. COMMD7 (COMM domain-containing protein 7) interacts with COMMD1 via its COMM domain. It also associates with the NF-kappa-B complex and suppresses its transcriptional activity.

Gene ID: 149951