TWF1 antibody (pTyr321) (AbBy Fluor® 488)

Catalog No. ABIN879488

The Rabbit Polyclonal anti-TWF1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect TWF1 in samples from Human.

Quick Overview for TWF1 antibody (pTyr321) (AbBy Fluor® 488) (ABIN879488)

Target: TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWF1 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TWF1 Antibody (AbBy Fluor® 488)

Binding Specificity: pTyr321

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human TWF1 around the phosphorylation site of Tyr321

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TWF1

Target: TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))

Alternative Name: PTK9

Background:

Synonyms: PTK9 Tyr321, PTK9 Y321, p-PTK9 Tyr321, p-TWF1Y321, A6, A6 protein tyrosine kinase, Protein A6, Protein tyrosine kinase 9, PTK9, PTK9 protein tyrosine kinase 9, TWF 1, TWF1, Twinfilin 1, Twinfilin actin binding protein, homolog 1, Twinfilin, Twinfilin, actin-binding protein, homolog 1 Drosophila, Twinfilin, Drosophila, homolog of, 1, TWF1_HUMAN, Twinfilin-1.

Background: PTK9 is an actin-binding protein involved in motile and morphological processes. It inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. PTK9 seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.

Gene ID: 5756

Pathways: Regulation of Actin Filament Polymerization, Maintenance of Protein Location