HSP70 antibody (pTyr525) (AbBy Fluor® 488)

Catalog No. ABIN879829

Product Details anti-HSP70 Antibody (AbBy Fluor® 488)

Target: HSP70 (Heat Shock Protein 70 (HSP70))

Binding Specificity: pTyr525

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP70 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Dog,Cow,Sheep,Pig,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HSP70 around the phosphorylation site of Tyr525

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HSP70

Target: HSP70 (Heat Shock Protein 70 (HSP70))

Alternative Name: HSP70 (HSP70 Products)

Background:

Synonyms: HSP70 phospho Tyr525, HSP70 phospho Y525, p-HSP70 Tyr525, p-HSP70 Y525, HSP70, HSP-70, HSP 70, Heat shock 70 kDa protein 1, heat shock 70 kDa protein 1A, Heat shock 70 kDa protein 1B, Heat shock induced protein, heat shock protein 70, HSP70 1, HSP70 2, HSP70.1, HSP72, HSPA1, HSPA1A, HSPA1B, XXbac BCX40G17.3 001, Heat shock 70 kDa protein 1A/1B, HSP71_HUMAN, Hspa1a, Hsp70-1, HSP72, Hspa1, Hspa1b, Heat shock 70 kDa protein 1A/1B, shock 70 kDa protein 1/2, HSP70-1/HSP70-2, HSP70.1/HSP70.2.

Background: This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008].

Gene ID: 3303, 3304