CDC16 antibody (AA 301-400) (Biotin)

Catalog No. ABIN882943

This Rabbit Polyclonal antibody specifically detects CDC16 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CDC16 antibody (AA 301-400) (Biotin) (ABIN882943)

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC16 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CDC16 Antibody (Biotin)

Binding Specificity: AA 301-400

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human APC6/CDC16

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CDC16

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Alternative Name: CDC16

Background:

Synonyms: ANAPC6, Anaphase promoting complex subunit 6, Anaphase-promoting complex subunit 6, Apc 6, APC6, CDC 16, CDC16 cell division cycle 16 S. cerevisiae homolog, CDC16, CDC16 homolog, CDC16 protein, CDC16_HUMAN, CDC16Hs, Cell division cycle 16 homolog, Cell division cycle protein 16 homolog, CUT9, Cyclosome subunit 6.

Background: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Gene ID: 8881

Pathways: Regulation of Actin Filament Polymerization