CCDC138 antibody (AA 551-665) (HRP)

Catalog No. ABIN887232

This anti-CCDC138 antibody is a Rabbit Polyclonal antibody detecting CCDC138 in WB, ELISA, IHC (fro) and IHC (p). Suitable for Human.

Quick Overview for CCDC138 antibody (AA 551-665) (HRP) (ABIN887232)

Target: CCDC138 (Coiled-Coil Domain Containing 138 (CCDC138))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC138 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CCDC138 Antibody (HRP)

Binding Specificity: AA 551-665

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC138

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC138

Target: CCDC138 (Coiled-Coil Domain Containing 138 (CCDC138))

Alternative Name: CCDC138

Background:

Synonyms: CCDC 138, CCDC138, Coiled coil domain containing 138, Coiled coil domain containing protein 138, coiled-coil domain containing 138, FLJ 32745, FLJ32745, CC138_HUMAN.

Background: CCDC138, also known as FLJ32745, is a 685 amino acid protein expressed as two isoforms produced by alternative splicing. The gene that encodes CCDC138 maps to human chromosome 2q12.3. The second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Gene ID: 165055

Pathways: BCR Signaling