DAB2IP antibody (PE-Cy5.5)

Catalog No. ABIN893378

The Rabbit Polyclonal anti-DAB2IP antibody has been validated for WB. It is suitable to detect DAB2IP in samples from Human, Mouse, Rat, Guinea Pig, Cow, Dog and Pig.

Quick Overview for DAB2IP antibody (PE-Cy5.5) (ABIN893378)

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAB2IP antibody is conjugated to PE-Cy5.5

Application: Western Blotting (WB)

Product Details anti-DAB2IP Antibody (PE-Cy5.5)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DAB2IP

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DAB2IP

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Alternative Name: DAB2IP

Background:

Synonyms: AF9Q34, AIP1, ASK interacting protein, DAB2P_HUMAN, ASK interacting protein 1, ASK1 interacting protein 1, DAB2 interacting protein, DAB2 interaction protein, DAB2P, DIP1/2, Disabled homolog 2 interacting protein, DOC 2/DAB2 interactive protein, FLJ39072, KIAA1743, nGAP like protein.

Background: DAB2IP is a Ras GTPase-activating protein (GAP) that acts as a tumor suppressor gene and is inactivated by methylation in prostate and breast cancers. It also interacts with MAP3K5 to disrupt the association of MAP3K5 with the inhibitory 14-3-3 complex.

Molecular Weight: 118kDa

Gene ID: 153090

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Tube Formation