Dynamitin antibody (AA 65-150) (Cy5.5)

Catalog No. ABIN894643

This Rabbit Polyclonal antibody specifically detects Dynamitin in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for Dynamitin antibody (AA 65-150) (Cy5.5) (ABIN894643)

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dynamitin antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Dynamitin Antibody (Cy5.5)

Binding Specificity: AA 65-150

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Dynamitin/DCTN2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Dynamitin

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Alternative Name: DCTN2

Background:

Synonyms: 50 kD dynein associated polypeptide, 50 kDa dynein associated polypeptide, 50 kDa dynein-associated polypeptide, DCTN-50, DCTN2, DCTN2_HUMAN, DCTN50, dynactin 2 p50, dynactin 2, dynactin complex 50 kD subunit, Dynactin complex 50 kDa subunit, Dynactin subunit 2, p50 dynamitin, RBP50.

Background: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

Gene ID: 10540

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization