FOXP3 antibody (AbBy Fluor® 647)

Catalog No. ABIN897610

This Rabbit Polyclonal antibody specifically detects FOXP3 in IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FOXP3 antibody (AbBy Fluor® 647) (ABIN897610)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP3 antibody is conjugated to AbBy Fluor® 647

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FOXP3 Antibody (AbBy Fluor® 647)

Specificity: Excitation / Emission Wavelengths: 652nm/668nm

Cross-Reactivity: Rat (Rattus)

Purification: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human FoxP3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4 °C for 12 months

Expiry Date: 12 months

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: FoxP3

Background: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Molecular Weight: 47kDa

Gene ID: 50943

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation