GPRIN2 antibody (AA 251-350) (Biotin)

Catalog No. ABIN899612

The Rabbit Polyclonal anti-GPRIN2 antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect GPRIN2 in samples from Human.

Quick Overview for GPRIN2 antibody (AA 251-350) (Biotin) (ABIN899612)

Target: GPRIN2 (G Protein Regulated Inducer of Neurite Outgrowth 2 (GPRIN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPRIN2 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GPRIN2 Antibody (Biotin)

Binding Specificity: AA 251-350

Predicted Reactivity: Human,Mouse,Rat,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPRIN2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GPRIN2

Target: GPRIN2 (G Protein Regulated Inducer of Neurite Outgrowth 2 (GPRIN2))

Alternative Name: GPRIN2

Background:

Synonyms: G protein-regulated inducer of neurite outgrowth 2, Gm286, G protein-regulated inducer of neurite outgrowth 2, GPRIN2, GRIN2, GRIN2_HUMAN, MGC15171, mKIAA0514, RGD1308922.

Background: G protein-coupled receptors (GPCRs) represent a large superfamily of cell-surface receptors that are involved in a multitude of physiological processes such as perception of sensory information, modulation of synaptic transmission, hormone release/actions, regulation of cell contraction/migration and cell growth/differentiation. GPCRs interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. GRIN2 (G protein-regulated inducer of neurite outgrowth 2), also known as GPRIN2, is a 458 amino acid protein that is expressed in cerebellum and is thought to play a role in neurite outgrowth. GRIN2 interacts with activated G?oand G?, and is encoded by a gene that maps to human chromosome 10q11.22.

Gene ID: 9721