GZMK antibody (Cy5.5)

Catalog No. ABIN899671

This Rabbit Polyclonal antibody specifically detects GZMK in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GZMK antibody (Cy5.5) (ABIN899671)

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GZMK antibody is conjugated to Cy5.5

Application: Western Blotting (WB)

Product Details anti-GZMK Antibody (Cy5.5)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Granzyme K

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GZMK

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Alternative Name: Granzyme K

Background:

Synonyms: Fragmentin 3, Fragmentin-3, Fragmentin3, GRAK_HUMAN, Granzyme 3, Granzyme K, Granzyme K precursor, Granzyme-3, Granzyme3, GranzymeK, GZMK, NK TRYP 2, NK TRYP2, NK tryptase 2, NK-TRYP-2, NK-tryptase-2, NKTRYP2, Serine protease granzyme 3, TRYP 2, TRYP2, Tryptase II, TryptaseII.

Background: This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008].

Gene ID: 3003