IL27 Receptor alpha antibody (PE-Cy5.5)

Catalog No. ABIN902373

This anti-IL27 Receptor alpha antibody is a Rabbit Polyclonal antibody detecting IL27 Receptor alpha in WB. Suitable for Human, Mouse and Rat.

Quick Overview for IL27 Receptor alpha antibody (PE-Cy5.5) (ABIN902373)

Target: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL27 Receptor alpha antibody is conjugated to PE-Cy5.5

Application: Western Blotting (WB)

Product Details anti-IL27 Receptor alpha Antibody (PE-Cy5.5)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-27RA

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IL27 Receptor alpha

Target: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Alternative Name: IL-27R

Background:

Synonyms: CRL1, TCCR, WSX1, IL27R, IL-27RA, zcytor1, Interleukin-27 receptor subunit alpha, IL-27 receptor subunit alpha, IL-27R subunit alpha, IL-27R-alpha, Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor, IL27RA, UNQ296/PRO336

Background: Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.

Molecular Weight: 70kDa

Gene ID: 9466

UniProt: Q6UWB1

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response