MRPL11 antibody (AA 31-130) (HRP)

Catalog No. ABIN906455

The Rabbit Polyclonal anti-MRPL11 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect MRPL11 in samples from Human.

Quick Overview for MRPL11 antibody (AA 31-130) (HRP) (ABIN906455)

Target: MRPL11 (Mitochondrial Ribosomal Protein L11 (MRPL11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL11 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MRPL11 Antibody (HRP)

Binding Specificity: AA 31-130

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Mitochondrial ribosomal protein L11

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MRPL11

Target: MRPL11 (Mitochondrial Ribosomal Protein L11 (MRPL11))

Alternative Name: Mitochondrial ribosomal protein L11

Background:

Synonyms: 39S ribosomal protein L11, mitochondrial, CGI113, CGI 113, L11mt, MRP L11, MRP-L11, RM11_HUMAN.

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq, Jul 2008].

Gene ID: 65003