NET1 antibody (AA 331-430) (AbBy Fluor® 647)

Catalog No. ABIN908028

Product Details anti-NET1 Antibody (AbBy Fluor® 647)

Target: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Binding Specificity: AA 331-430

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NET1 antibody is conjugated to AbBy Fluor® 647

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NET1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-NET1 antibody (AbBy Fluor® 647) (ABIN908028)

Wiesbauer, Wollhofen, Vasic, Schilcher, Jacak, Klar: "Nano-Anchors with Single Protein Capacity Produced with STED Lithography." in: Nano letters, Vol. 13, Issue 11, pp. 5672-8, (2013) (PubMed).

Target Details for NET1

Target: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Alternative Name: NET1 (NET1 Products)

Background:

Synonyms: mNET1, ARHGEF8, GLYT2, Guanine nucleotide regulatory protein oncogene, NET1A, Neuroepithelial cell transforming gene 1, p65 Net1 proto oncogene, Rho guanine nucleotide exchange factor GEF 8, ARHG8_HUMAN.

Background: This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Gene ID: 10276

Pathways: Neurotrophin Signaling Pathway