NOG antibody (AA 28-130) (Biotin)

Catalog No. ABIN908618

The Rabbit Polyclonal anti-NOG antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect NOG in samples from Mouse and Rat.

Quick Overview for NOG antibody (AA 28-130) (Biotin) (ABIN908618)

Target: NOG (Noggin (NOG))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOG antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NOG Antibody (Biotin)

Binding Specificity: AA 28-130

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Noggin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NOG

Target: NOG (Noggin (NOG))

Alternative Name: Noggin

Background:

Synonyms: NOG, NOGG_HUMAN, Noggin, SYM 1, SYM1, Symphalangism 1 proximal, Synostoses multiple syndrome 1, SYNS 1, SYNS1.

Background: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 (PubMed:21976273).

Gene ID: 9241

UniProt: Q13253

Pathways: Stem Cell Maintenance, Tube Formation