PDGF-BB Homodimer (AA 151-241) antibody (AbBy Fluor® 488)

Catalog No. ABIN910536

This anti- antibody is a Rabbit Polyclonal antibody detecting in WB, IF (cc) and IF (p). Suitable for Human, Mouse, Rat and Chicken.

Quick Overview for PDGF-BB Homodimer (AA 151-241) antibody (AbBy Fluor® 488) (ABIN910536)

Target: PDGF-BB Homodimer

Reactivity: Human, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details

Binding Specificity: AA 151-241

Cross-Reactivity: Chicken, Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDGF-B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: PDGF-BB Homodimer

Alternative Name: PDGFBB

Background:

Synonyms: PDGF BB, PDGF-BB, platelet derived growth factor-BB, Becaplermin, C sis, FLJ12858, Oncogene SIS, PDG B chain, PDGB, PDGF 2, PDGF B, PDGF B chain, PDGF2, PDGFB, PDGFB/COL1A1 fusion gene, Platelet derived growth factor 2, Platelet derived growth factor B chain, Platelet derived growth factor beta, Platelet derived growth factor beta polypeptide, Simian sarcoma viral v sis oncogene homolog, SIS, SSV, V sis platelet derived growth factor beta polypeptide.

Background: Platelet Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B, the dimers being connected by disulfide bonds. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.

Gene ID: 5155