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beta Actin antibody (Cytoplasmic Domain)

The Mouse Monoclonal anti-beta Actin antibody has been validated for WB, IHC (p) and IHC (fro). It is suitable to detect beta Actin in samples from Human, Mouse, Rat, Chicken, Rabbit, Pig and Zebrafish (Danio rerio). There are 5+ publications available.
Catalog No. ABIN920525

Quick Overview for beta Actin antibody (Cytoplasmic Domain) (ABIN920525)

Target

See all beta Actin (ACTB) Antibodies
beta Actin (ACTB) (Actin, beta (ACTB))

Reactivity

  • 196
  • 137
  • 116
  • 54
  • 44
  • 42
  • 40
  • 27
  • 27
  • 24
  • 17
  • 15
  • 11
  • 10
  • 7
  • 7
  • 6
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat, Chicken, Rabbit, Pig, Zebrafish (Danio rerio)

Host

  • 117
  • 101
  • 5
  • 1
  • 1
Mouse

Clonality

  • 112
  • 111
Monoclonal

Conjugate

  • 159
  • 11
  • 11
  • 9
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This beta Actin antibody is un-conjugated

Application

  • 191
  • 79
  • 77
  • 47
  • 47
  • 44
  • 31
  • 27
  • 13
  • 13
  • 6
  • 6
  • 6
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

4C2
  • Binding Specificity

    • 41
    • 17
    • 16
    • 15
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cytoplasmic Domain

    Specificity

    The epitope recognized by alpha-SM1 is highly conserved. The antibody therefore cross-reacts with many species including protochordates, lower craniates and mammals.

    Characteristics

    Cytoskeletal

    Isotype

    IgG1
  • Restrictions

    For Research Use only
  • Storage

    4 °C/-20 °C
  • Roeles, Tsiavaliaris: "Actin-microtubule interplay coordinates spindle assembly in human oocytes." in: Nature communications, Vol. 10, Issue 1, pp. 4651, (2020) (PubMed).

    Gallant, Appel, Graceffa, Leavis, Lin, Gunning, Schevzov, Chaponnier, DeGnore, Lehman, Morgan: "Tropomyosin variants describe distinct functional subcellular domains in differentiated vascular smooth muscle cells." in: American journal of physiology. Cell physiology, Vol. 300, Issue 6, pp. C1356-65, (2011) (PubMed).

    Dugina, Zwaenepoel, Gabbiani, Clément, Chaponnier: "Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity." in: Journal of cell science, Vol. 122, Issue Pt 16, pp. 2980-8, (2009) (PubMed).

    Bassell, Zhang, Byrd, Femino, Singer, Taneja, Lifshitz, Herman, Kosik: "Sorting of beta-actin mRNA and protein to neurites and growth cones in culture." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 18, Issue 1, pp. 251-65, (1998) (PubMed).

    Vandekerckhove, Weber: "At least six different actins are expressed in a higher mammal: an analysis based on the amino acid sequence of the amino-terminal tryptic peptide." in: Journal of molecular biology, Vol. 126, Issue 4, pp. 783-802, (1979) (PubMed).

  • Target

    beta Actin (ACTB) (Actin, beta (ACTB))

    Alternative Name

    Actin beta

    Pathways

    Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction
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