Caveolin-1 antibody

Catalog No. ABIN920746

This Mouse Monoclonal antibody specifically detects Caveolin-1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Caveolin-1 antibody (ABIN920746)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caveolin-1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 4D6

Product Details anti-Caveolin-1 Antibody

Specificity: Caveolin-1 is a major structural component of caveolae which are vasicular invaginations present on the plasma membrane of different cell types. It plays a regulatory role in several signalling pathways and is reported to be most abundantly expressed in terminally differentiated mesenchymal cells such as smooth muscle cells, adipocytes, endothelial cells and fibroblasts.

Characteristics: Positive Control: Immunohistochemistry: Colon. Western blot: MG-63 cell line. Cellular Localization: Cytoplasmic and membrane.

Immunogen: Prokaryotic recombinant protein containing part of the N-terminus domain of the human Caveolin-1 molecule.

Isotype: IgG2a kappa

Application Details

Application Notes: Immunohistochemistry: Paraffin sections. Use at a 1:200 dilution. Use a high- temperature antigen unmasking technique with 60-minute primary antibody incubation at 25°C and standard ABC technique. Western blot: Use at ~ 1:4,000 dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 mL of liquid tissue culture supernatant containing monoclonal antibody with 15 mM sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Alternative Name: Caveolin-1

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals