NAPA antibody (N-Term)

Catalog No. ABIN926040

This anti-NAPA antibody is a Rabbit Polyclonal antibody detecting NAPA in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio) and Xenopus laevis.

Quick Overview for NAPA antibody (N-Term) (ABIN926040)

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAPA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NAPA Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Frog, Zebrafish (Brachydanio rerio)

Immunogen: NAPA antibody was raised in rabbit using the N terminal of NAPA as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

NAPA Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this NAPA antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for NAPA

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Alternative Name: NAPA

Background: The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. Synonyms: Polyclonal NAPA antibody, Anti-NAPA antibody, N-ethylmaleimide-sensitive factor attachment protein, alpha antibody.

Pathways: Synaptic Vesicle Exocytosis, Asymmetric Protein Localization