SCARB2 antibody (N-Term)

Catalog No. ABIN926775

This anti-SCARB2 antibody is a Rabbit Polyclonal antibody detecting SCARB2 in WB. Suitable for Human.

Quick Overview for SCARB2 antibody (N-Term) (ABIN926775)

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCARB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SCARB2 Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: SCARB2 antibody was raised in rabbit using the N terminal of SCARB2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

SCARB2 Blocking Peptide, (ABIN936414), is also available for use as a blocking control in assays to test for specificity of this SCARB2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SCARB2

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Alternative Name: SCARB2

Background: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Synonyms: Polyclonal SCARB2 antibody, Anti-SCARB2 antibody, scavenger receptor class B, member 2 antibody, AMRF antibody, CD36L2 antibody, HLGP85 antibody, LIMPII antibody, SR-BII antibody.