TNIP1 antibody (N-Term)

Catalog No. ABIN926782

This Rabbit Polyclonal antibody specifically detects TNIP1 in WB. It exhibits reactivity toward Human.

Quick Overview for TNIP1 antibody (N-Term) (ABIN926782)

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNIP1 Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: TNIP1 antibody was raised in rabbit using the N terminal of TNIP1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

TNIP1 Blocking Peptide, (ABIN936397), is also available for use as a blocking control in assays to test for specificity of this TNIP1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TNIP1

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Alternative Name: TNIP1

Background: TNIP1 interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. TNIP1 increases cell surface CD4(T4) antigen expression. TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. TNIP1 may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. Synonyms: Polyclonal TNIP1 antibody, Anti-TNIP1 antibody, TNFAIP3 interacting protein 1 antibody, ABIN-1 antibody, KIAA0113 antibody, NAF1 antibody, VAN antibody.

Pathways: Activation of Innate immune Response