TRAF4 antibody (Middle Region)

Catalog No. ABIN926937

This anti-TRAF4 antibody is a Rabbit Polyclonal antibody detecting TRAF4 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio) and Xenopus laevis.

Quick Overview for TRAF4 antibody (Middle Region) (ABIN926937)

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRAF4 Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Zebrafish (Brachydanio rerio), Frog, Dog (Canine)

Purification: Purified

Immunogen: TRAF4 antibody was raised in rabbit using the middle region of TRAF4 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TRAF4 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this TRAF4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Alternative Name: TRAF4

Background: TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Synonyms: Polyclonal TRAF4 antibody, Anti-TRAF4 antibody, TNF receptor-associated factor 4 antibody, CART1 antibody, MLN62 antibody, RNF83 antibody.