HAND2 antibody (C-Term)

Catalog No. ABIN927294

This anti-HAND2 antibody is a Rabbit Polyclonal antibody detecting HAND2 in WB. Suitable for Human and Mouse.

Quick Overview for HAND2 antibody (C-Term) (ABIN927294)

Target: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAND2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HAND2 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Hand2 antibody was raised in rabbit using the C terminal of Hand2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Hand2 Blocking Peptide, (ABIN937519), is also available for use as a blocking control in assays to test for specificity of this Hand2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for HAND2

Target: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Alternative Name: Hand2

Background: Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Synonyms: Polyclonal Hand2 antibody, Anti-Hand2 antibody, heart and neural crest derivatives expressed transcript 2 antibody, AI225906 antibody, AI661148 antibody, Ehand2 antibody, Hed antibody, Th2 antibody, Thing2 antibody, bHLHa26 antibody, dHAND antibody.

Pathways: Tube Formation, Feeding Behaviour