ESRRA antibody (C-Term)

Catalog No. ABIN927364

Product Details anti-ESRRA Antibody

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRRA antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Esrra antibody was raised in rabbit using the C terminal of Esrra as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Esrra Blocking Peptide, catalog no. 33R-1216, is also available for use as a blocking control in assays to test for specificity of this Esrra antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Alternative Name: Esrra (ESRRA Products)

Background: Esrra binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. It can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. It binds to the C1 region of the lactoferrin gene promoter. It requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Synonyms: Polyclonal Esrra antibody, Anti-Esrra antibody, estrogen related receptor, alpha antibody, ERRalpha antibody, Err1 antibody, Estrra antibody, Nr3b1 antibody.

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha