SIRT4 antibody (Middle Region)

Catalog No. ABIN927380

The Rabbit Polyclonal anti-SIRT4 antibody has been validated for WB and IHC. It is suitable to detect SIRT4 in samples from Human, Mouse, Rat, Cow and Pig.

Quick Overview for SIRT4 antibody (Middle Region) (ABIN927380)

Target: SIRT4 (Sirtuin 4 (SIRT4))

Reactivity: Human, Mouse, Rat, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SIRT4 Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Pig (Porcine)

Purification: Purified

Immunogen: SIRT4 antibody was raised in rabbit using the middle region of SIRT4 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SIRT4 Blocking Peptide, (ABIN5616158), is also available for use as a blocking control in assays to test for specificity of this SIRT4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SIRT4

Target: SIRT4 (Sirtuin 4 (SIRT4))

Alternative Name: SIRT4

Background: SIRT4 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT4 is included in class IV of the sirtuin family. Synonyms: Polyclonal SIRT4 antibody, Anti-SIRT4 antibody, sirtuin, silent mating type information regulation 2 homolog 4, S. cerevisiae antibody, MGC130046 antibody, MGC130047 antibody, MGC57437 antibody, SIR2L4 antibody, sirtuin 4 antibody.

Pathways: Negative Regulation of Hormone Secretion