TANK antibody (TRAF Family Member-Associated NFKB Activator) (N-Term)

Details for Product anti-TANK Antibody No. ABIN927715
Antigen
Epitope
N-Term
18
18
11
11
9
7
5
4
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Chicken, Dog (Canine)
130
50
46
8
7
6
5
4
4
4
2
1
1
Host
Rabbit
125
3
2
1
1
Clonality
Polyclonal
Conjugate
This TANK antibody is un-conjugated
7
6
6
4
4
4
2
2
2
2
2
2
1
1
1
1
1
Application
Western Blotting (WB)
110
47
38
24
19
18
13
12
7
5
3
3
2
1
Options
Immunogen TANK antibody was raised in rabbit using the N terminal of TANK as the immunogen
Cross-Reactivity Mouse (Murine), Rat (Rattus), Cow (Bovine), Chicken, Dog (Canine)
Purification Purified
Antigen
Alternative Name TANK (TANK Antibody Abstract)
Background The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. Synonyms: Polyclonal TANK antibody, Anti-TANK antibody, TRAF family member-associated NFKB activator antibody, I-TRAF antibody, TRAF2 antibody.
Pathways p53 Signaling, TLR Signaling, Activation of Innate immune Response
Application Notes WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.
Comment

TANK Blocking Peptide, catalog no. 33R-2027, is also available for use as a blocking control in assays to test for specificity of this TANK antibody

Restrictions For Research Use only
Format Lyophilized
Concentration Lot specific
Buffer Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage RT/-20 °C
Storage Comment Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
Supplier Images
Image no. 1 for anti-TRAF Family Member-Associated NFKB Activator (TANK) (N-Term) antibody (ABIN927715) TANK antibody used at 0.2-1 ug/ml to detect target protein.