BACE1 antibody (Middle Region)

Catalog No. ABIN928119

This anti-BACE1 antibody is a Rabbit Polyclonal antibody detecting BACE1 in WB. Suitable for Human and Mouse.

Quick Overview for BACE1 antibody (Middle Region) (ABIN928119)

Target: BACE1 (Beta-secretase 1 (BACE1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BACE1 Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Bace1 antibody was raised in rabbit using the middle region of Bace1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: Bace1

Background: Bace1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Bace1 cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Synonyms: Polyclonal Bace1 antibody, Anti-Bace1 antibody, beta-site APP cleaving enzyme 1 antibody, C76936 antibody.