IL17A
Reactivity: Human
FACS
Host: Mouse
Monoclonal
9F9
PE
Application Notes
WB: 0.2-1 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Concentration
Lot specific
Buffer
Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice
Avoid repeated freeze/thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
Target
Interleukin 17a (IL17A)
(Interleukin 17A (IL17A))
Alternative Name
IL17A
Background
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. Synonyms: Polyclonal IL17A antibody, Anti-IL17A antibody, interleukin 17A antibody, CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody.