CORT antibody (N-Term)

Catalog No. ABIN929265

Cited in 1 publication. The Rabbit Polyclonal anti-CORT antibody (ABIN929265) specifically detects CORT in WB. The antibody is reactive with Human samples.

Quick Overview for CORT antibody (N-Term) (ABIN929265)

Target: CORT (Cortistatin (CORT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CORT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CORT Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: CORT antibody was raised in rabbit using the N terminal of CORT as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CORT Blocking Peptide, (ABIN5612967), is also available for use as a blocking control in assays to test for specificity of this CORT antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

References for anti-CORT antibody (ABIN929265)

DeVries, Holbrook, Winters, Jawor: "Non-breeding gonadal testosterone production of male and female northern cardinals (Cardinalis cardinalis) following GnRH challenge." in: General and comparative endocrinology, Vol. 174, Issue 3, pp. 370-8, (2011) (PubMed).

Target Details for CORT

Target: CORT (Cortistatin (CORT))

Alternative Name: CORT

Background: This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739. Synonyms: Polyclonal CORT antibody, Anti-CORT antibody, cortistatin antibody, CST-14 antibody, CST-17 antibody, CST-29 antibody.