MAX antibody

Catalog No. ABIN932461

This Mouse Monoclonal antibody specifically detects MAX in DB. It exhibits reactivity toward Human.

Quick Overview for MAX antibody (ABIN932461)

Target: MAX (MYC Associated Factor X (MAX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAX antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 73C5a

Product Details anti-MAX Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: MAX antibody was raised in mouse using recombinant Human Helix-Loop-Helix Zipper Protein (Max)

Isotype: IgG2b

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: MAX antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for MAX

Target: MAX (MYC Associated Factor X (MAX))

Alternative Name: MAX

Background: Protein max is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxl1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E-box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown. Synonyms: Monoclonal MAX antibody, Anti-MAX antibody, MYC associated factor X antibody.

Pathways: Mitotic G1-G1/S Phases