FCAR
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB21753
unconjugated
Application Notes
FC: 10 µg/mL, IF: 10 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Concentration
Lot specific
Buffer
Supplied in PBS containing 0.1 % sodium azide as a preservative
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
-20 °C/-80 °C
Storage Comment
Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.
Target
FCAR
(Fc Fragment of IgA, Receptor For (FCAR))
Alternative Name
CD89
Background
CD89 is a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Synonyms: Monoclonal CD89 antibody, Anti-CD89 antibody, CD 89 antibody, CD-89 antibody, Fc fragment of IgA receptor antibody, FCAR antibody, Cluster of Differentiation 89 antibody, CD 89 antibody.