APC antibody

Catalog No. ABIN933873

The Rat Monoclonal anti-APC antibody (Clone KT44) (ABIN933873) specifically detects APC in WB and IF. The antibody is reactive with Mouse samples.

Quick Overview for APC antibody (ABIN933873)

Target: APC (Adenomatous Polyposis Coli (APC))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This APC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: KT44

Product Details anti-APC Antibody

Purification: Protein A affinity chromatography

Immunogen: APC protein antibody was raised in Rat using GST fusion protein having the APC region A as the immunogen.

Isotype: IgG2a

Application Details

Application Notes: IF: 10 µg/mL, WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Supplied in PBS containing 0.1 % sodium azide as a preservative

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C/-80 °C

Storage Comment: Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.

Target Details for APC

Target: APC (Adenomatous Polyposis Coli (APC))

Alternative Name: APC

Background: APC is classified as a tumor suppressor gene. Tumor suppressor genes prevent the uncontrolled growth of cells that may result in cancerous tumors. The protein made by the APC gene plays a critical role in several cellular processes that determine whether a cell may develop into a tumor. The APC protein helps control how often a cell divides, how it attaches to other cells within a tissue, or whether a cell moves within or away from a tissue. This protein also helps ensure that the chromosome number in cells produced through cell division is correct. Synonyms: Monoclonal APC protein antibody, Anti-APC protein antibody, Adenomatous polyposis coli protein antibody.

Pathways: WNT Signaling, Stem Cell Maintenance, Cell-Cell Junction Organization