PFKFB3 antibody (AA 1-520)

Catalog No. ABIN948248

The Rabbit Polyclonal anti-PFKFB3 antibody has been validated for WB and IP. It is suitable to detect PFKFB3 in samples from Human. There is 1 publication available.

Quick Overview for PFKFB3 antibody (AA 1-520) (ABIN948248)

Target: PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKFB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PFKFB3 Antibody

Binding Specificity: AA 1-520

Purpose: Rabbit polyclonal antibody raised against a full-length human PFKFB3 protein.

Sequence: MPLELTQSRV QKIWVPVDHR PSLPRSCGPK LTNSPTVIVM VGLPARGKTY ISKKLTRYLN WIGVPTKVFN VGEYRREAVK QYSSYNFFRP DNEEAMKVRK QCALAALRDV KSYLAKEGGQ IAVFDATNTT RERRHMILHF AKENDFKAFF IESVCDDPTV VASNIMEVKI SSPDYKDCNS AEAMDDFMKR ISCYEASYQP LDPDKCDRDL SLIKVIDVGR RFLVNRVQDH IQSRIVYYLM NIHVQPRTIY LCRHGENEHN LQGRIGGDSG LSSRGKKFAS ALSKFVEEQN LKDLRVWTSQ LKSTIQTAEA LRLPYEQWKA LNEIDAGVCE ELTYEEIRDT YPEEYALREQ DKYYYRYPTG ESYQDLVQRL EPVIMELERQ ENVLVICHQA VLRCLLAYFL DKSAEEMPYL KCPLHTVLKL TPVAYGCRVE SIYLNVESVC THRERSEDAK KGPNPLMRRN SVTPLASPEP TKKPRINSFE EHVASTSAAL PSCLPPEVPT QLPGQNMKGS RSSADSSRKH

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: PFKFB3 (NP_004557.1, 1 a.a. ~ 520 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: No additive

Preservative: Without preservative

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PFKFB3 antibody (ABIN948248)

Mendoza, Pocceschi, Kong, Leeper, Caro, Limesand, Burd: "Control of Glycolytic Flux by AMP-Activated Protein Kinase in Tumor Cells Adapted to Low pH." in: Translational oncology, Vol. 5, Issue 3, pp. 208-16, (2012) (PubMed).

Target Details for PFKFB3

Target: PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))

Alternative Name: PFKFB3

Background: Full Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Synonyms: IPFK2,PFK2

Gene ID: 5209

NCBI Accession: NM_004566

Pathways: AMPK Signaling, Regulation of Carbohydrate Metabolic Process