MT-ATP6 antibody (C-Term, Subunit alpha)

Catalog No. ABIN950556

This anti-MT-ATP6 antibody is a Rabbit Polyclonal antibody detecting MT-ATP6 in WB, EIA and IHC (p). Suitable for Human.

Quick Overview for MT-ATP6 antibody (C-Term, Subunit alpha) (ABIN950556)

Target: MT-ATP6 (Mitochondrially Encoded ATP Synthase 6 (MT-ATP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MT-ATP6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MT-ATP6 Antibody

Binding Specificity: AA 483-512, C-Term, Subunit alpha

Specificity: This antibody reacts to ATP synthase subunit alpha.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 483~512 amino acids from the C-terminal region of human ATP5A1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MT-ATP6

Target: MT-ATP6 (Mitochondrially Encoded ATP Synthase 6 (MT-ATP6))

Alternative Name: ATP Synthase Subunit alpha

Background: This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core.Synonyms: ATP5A, ATP5A1, ATP5AL2, ATPM, Complex V alpha subunit, F1F0 ATP synthase alpha subunit, mitochondrial ATP synthase subunit alpha

Gene ID: 498

NCBI Accession: NP_001001937

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process