Glucuronidase beta antibody (Middle Region)

Catalog No. ABIN950654

The Rabbit Polyclonal anti-Glucuronidase beta antibody has been validated for WB, FACS, IHC (p) and EIA. It is suitable to detect Glucuronidase beta in samples from Human.

Quick Overview for Glucuronidase beta antibody (Middle Region) (ABIN950654)

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucuronidase beta antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Glucuronidase beta Antibody

Binding Specificity: AA 341-371, Middle Region

Specificity: This antibody recognizes Human Beta-glucuronidase (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 341~371 amino acids from the Center region of Human Beta-glucuronidase Genename: GUSB

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Glucuronidase beta

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Alternative Name: beta-Glucuronidase

Background: The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993 [PubMed 7680524]). It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987 [PubMed 3468507]). The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7, MIM 253220).Synonyms: Beta-G1, GUSB

Molecular Weight: 74732 Da

Gene ID: 2990

NCBI Accession: NP_000172

Pathways: Glycosaminoglycan Metabolic Process