CHMP6 antibody (N-Term)

Catalog No. ABIN951505

This Rabbit Polyclonal antibody specifically detects CHMP6 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for CHMP6 antibody (N-Term) (ABIN951505)

Target: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CHMP6 Antibody

Binding Specificity: AA 1-3, N-Term

Specificity: This antibody detects human CHMP6 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 1-30aa) of human CHMP6.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CHMP6

Target: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Alternative Name: CHMP6

Background: CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PMID 16730941]).Synonyms: Charged multivesicular body protein 6, Chromatin-modifying protein 6, VPS20, Vacuolar protein sorting-associated protein 20

Gene ID: 79643

NCBI Accession: NP_078867