GUCA2B antibody (C-Term)

Catalog No. ABIN952662

Product Details anti-GUCA2B Antibody

Target: GUCA2B (Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))

Binding Specificity: AA 68-97, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCA2B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human GUCA2B (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 68-97 amino acids from the C-terminal region of human GUCA2B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GUCA2B

Target: GUCA2B (Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))

Alternative Name: GUCA2B (GUCA2B Products)

Background: Uroguanylin and guanylin (GUCA2A, MIM 139392), peptide homologs of the bacterial heat-stable enterotoxins (e.g., the E. coli ST toxin, STa), are endogenous activators of the guanylate cyclase-2C receptor (GUCY2C, MIM 601330), which synthesizes cyclic GMP (cGMP), a key component of several intracellular signal transduction pathways.Synonyms: GCAP-II, Guanylate cyclase C-activating peptide 2, Guanylate cyclase activator 2B, UGN, Uroguanylin

Molecular Weight: 12069 Da

Gene ID: 2981

NCBI Accession: NP_009033