KRT80 antibody (C-Term)

Catalog No. ABIN953034

Product Details anti-KRT80 Antibody

Target: KRT80 (Keratin 80 (KRT80))

Binding Specificity: AA 417-436, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT80 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to KRT80.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 417-436 amino acids from the C-terminal region of human KRT80

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KRT80

Target: KRT80 (Keratin 80 (KRT80))

Alternative Name: Keratin-80 (KRT80) (KRT80 Products)

Background: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.Synonyms: Cytokeratin-80, KB20, Keratin 80, Keratin type II cytoskeletal 80, Type II keratin-20

Molecular Weight: 50525 Da

Gene ID: 144501

NCBI Accession: NP_001074961