Msx2/Hox8 antibody (Middle Region)

Catalog No. ABIN953530

This Rabbit Polyclonal antibody specifically detects Msx2/Hox8 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Msx2/Hox8 antibody (Middle Region) (ABIN953530)

Target: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Msx2/Hox8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Msx2/Hox8 Antibody

Binding Specificity: AA 119-148, Middle Region

Specificity: This antibody recognizes Human MSX2 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human MSX2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Msx2/Hox8

Target: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Alternative Name: MSX2

Background: This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.Synonyms: HOX-8, HOX8, Homeobox protein MSX-2, MSX-2

Molecular Weight: 28897 Da

Gene ID: 4488

NCBI Accession: NP_002440