Oxytocin antibody (Middle Region)
Quick Overview for Oxytocin antibody (Middle Region) (ABIN953964)
Target
See all Oxytocin (OXT) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 19-48, Middle Region
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Specificity
- This antibody recognizes Human Ocytocin (Center). Other species not tested.
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Purification
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogen
- KLH conjugated synthetic peptide between 19~48 amino acids from the Central region of Human Ocytocin Genename: NEU1
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Oxytocin (OXT)
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Alternative Name
- Oxytocin
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Target Type
- Hormone
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Background
- There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.Synonyms: OXT, Ocytocin
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Molecular Weight
- 12722 Da
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Gene ID
- 5020
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NCBI Accession
- NP_000906
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Pathways
- Myometrial Relaxation and Contraction, Feeding Behaviour
Target
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